Cargando…

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

All women undergo the menopause transition (MT), a neuro-endocrinological process that impacts aging trajectories of multiple organ systems including brain. The MT occurs over time and is characterized by clinically defined stages with specific neurological symptoms. Yet, little is known of how this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mosconi, Lisa, Berti, Valentina, Dyke, Jonathan, Schelbaum, Eva, Jett, Steven, Loughlin, Lacey, Jang, Grace, Rahman, Aneela, Hristov, Hollie, Pahlajani, Silky, Andrews, Randolph, Matthews, Dawn, Etingin, Orli, Ganzer, Christine, de Leon, Mony, Isaacson, Richard, Brinton, Roberta Diaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190071/ https://www.ncbi.nlm.nih.gov/pubmed/34108509 http://dx.doi.org/10.1038/s41598-021-90084-y

Ejemplares similares

Sex and menopause impact (31)P-Magnetic Resonance Spectroscopy brain mitochondrial function in association with (11)C-PiB PET amyloid-beta load
por: Jett, Steven, et al.
Publicado: (2022)

Ovarian steroid hormones: A long overlooked but critical contributor to brain aging and Alzheimer’s disease
por: Jett, Steven, et al.
Publicado: (2022)

Sex and Gender Driven Modifiers of Alzheimer’s: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks
por: Rahman, Aneela, et al.
Publicado: (2019)

Endogenous and Exogenous Estrogen Exposures: How Women’s Reproductive Health Can Drive Brain Aging and Inform Alzheimer’s Prevention
por: Jett, Steven, et al.
Publicado: (2022)

Effects of sex and APOE ε4 genotype on brain mitochondrial high-energy phosphates in midlife individuals at risk for Alzheimer’s disease: A (31)Phosphorus MR spectroscopy study
por: Jett, Steven, et al.
Publicado: (2023)

Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study
por: Mosconi, Lisa, et al.
Publicado: (2018)

In vivo Brain Estrogen Receptor Expression By Neuroendocrine Aging And Relationships With Gray Matter Volume, Bio-Energetics, and Clinical Symptomatology
por: Mosconi, Lisa, et al.
Publicado: (2023)

Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer’s disease and dementia
por: Nerattini, Matilde, et al.
Publicado: (2023)

Associations of lifestyle and vascular risk factors with Alzheimer’s brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area
por: Walters, Michelle J, et al.
Publicado: (2018)

Systematic review of (31)P-magnetic resonance spectroscopy studies of brain high energy phosphates and membrane phospholipids in aging and Alzheimer's disease
por: Jett, Steven, et al.
Publicado: (2023)

Precision Medicine for Alzheimer’s Disease Prevention
por: Berkowitz, Cara L., et al.
Publicado: (2018)

Lifestyle and vascular risk effects on MRI-based biomarkers of Alzheimer’s disease: a cross-sectional study of middle-aged adults from the broader New York City area
por: Mosconi, Lisa, et al.
Publicado: (2018)

Utility of the NIH Toolbox for assessment of prodromal Alzheimer's disease and dementia
por: Hackett, Katherine, et al.
Publicado: (2018)

The clinical practice of risk reduction for Alzheimer’s disease: A precision medicine approach
por: Isaacson, Richard S., et al.
Publicado: (2018)

Correction: Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery
por: Mosconi, Lisa, et al.
Publicado: (2018)

Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery
por: Mosconi, Lisa, et al.
Publicado: (2017)

Mechanisms of Risk Reduction in the Clinical Practice of Alzheimer’s Disease Prevention
por: Schelke, Matthew W., et al.
Publicado: (2018)

Quantifying cerebrospinal fluid dynamics: A review of human neuroimaging contributions to CSF physiology and neurodegenerative disease
por: Mehta, Neel H., et al.
Publicado: (2022)

Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer’s: A Multi-Modality Brain Imaging Study
por: Matthews, Dawn C., et al.
Publicado: (2014)

Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseases
por: Wang, Yiwei, et al.
Publicado: (2020)

Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease
por: Li, Yi, et al.
Publicado: (2022)

Neurovascular Unit Dysfunction and Blood–Brain Barrier Hyperpermeability Contribute to Schizophrenia Neurobiology: A Theoretical Integration of Clinical and Experimental Evidence
por: Najjar, Souhel, et al.
Publicado: (2017)

Effectiveness of online education for recruitment to an Alzheimer's disease prevention clinical trial
por: Saif, Nabeel, et al.
Publicado: (2020)

Maternal transmission of Alzheimer's disease: Prodromal metabolic phenotype and the search for genes
por: Mosconi, Lisa, et al.
Publicado: (2010)

Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease
por: Mishra, Aarti, et al.
Publicado: (2018)

Menopausal oestrogens and breast cancer risk: an expanded case-control study.
por: Brinton, L. A., et al.
Publicado: (1986)

Informing Women on Menopause and Hormone Therapy: Know the Menopause a Multidisciplinary Project Involving Local Healthcare System
por: Donati, Serena, et al.
Publicado: (2013)

Measurement of neurodegeneration using a multivariate early frame amyloid PET classifier
por: Matthews, Dawn C., et al.
Publicado: (2022)

Tau PET following acute TBI: Off-target binding to blood products, tauopathy, or both?
por: Butler, Tracy, et al.
Publicado: (2022)

Association between menopausal hormone therapy and risk of neurodegenerative diseases: Implications for precision hormone therapy
por: Kim, Yu Jin, et al.
Publicado: (2021)

Ovarian cancer and menopausal hormone therapy in the NIH-AARP diet and health study
por: Trabert, B, et al.
Publicado: (2012)

Changes in androstenedione, dehydroepiandrosterone, testosterone, estradiol, and estrone over the menopausal transition
por: Kim, Catherine, et al.
Publicado: (2017)

Chronic vulvar pain in a cohort of post-menopausal women: Atrophy or Vulvodynia?
por: Mitro, Susanna D., et al.
Publicado: (2016)

A systematic review of menopause apps with an emphasis on osteoporosis
por: Paripoorani, Deborah, et al.
Publicado: (2023)

Dissociation of Down syndrome and Alzheimer's disease effects with imaging
por: Matthews, Dawn C., et al.
Publicado: (2016)

Effect of Menopausal Hormone Therapy on the Vaginal Microbiota and Genitourinary Syndrome of Menopause in Chinese Menopausal Women
por: Geng, Lulu, et al.
Publicado: (2020)

Factors related to the experience of menopausal symptoms in women prescribed tamoxifen
por: Moon, Zoe, et al.
Publicado: (2017)

Associations Between Repeated Measures of Urinary Phthalate Metabolites With Hormones and Timing of Natural Menopause
por: Ding, Ning, et al.
Publicado: (2023)

Commentary on guidelines on osteoporosis and menopause - Indian Menopause Society
por: Fenton, Anna
Publicado: (2013)

The relationship of menopausal symptoms with the type of menopause and lipid levels
por: Demir, Omer, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_abs33psh3si8eb86ddo8hjt10e