Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss

Patients with Alzheimer’s disease (AD) often have lower bone mass than healthy individuals. However, the mechanisms underlying this change remain elusive. Previously, we found that Tg2576 mice, an AD animal model that ubiquitously expresses Swedish mutant amyloid precursor protein (APP(swe)), shows...

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Detalles Bibliográficos
Autores principales: Guo, Hao-Han, Xiong, Lei, Pan, Jin-Xiu, Lee, Daehoon, Liu, Kevin, Ren, Xiao, Wang, Bo, Yang, Xiao, Cui, Shun, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190093/
https://www.ncbi.nlm.nih.gov/pubmed/34108442
http://dx.doi.org/10.1038/s41413-021-00146-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190093/
https://www.ncbi.nlm.nih.gov/pubmed/34108442
http://dx.doi.org/10.1038/s41413-021-00146-0

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