Molecular insight into isoform specific inhibition of PI3K-α and PKC-η with dietary agents through an ensemble pharmacophore and docking studies

Dietary compounds play an important role in the prevention and treatment of many cancers, although their specific molecular mechanism is not yet known. In the present study, thirty dietary agents were analyzed on nine drug targets through in silico studies. However, nine dietary scaffolds, such as s...

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Detalles Bibliográficos
Autores principales: Bhaskar, Baki Vijaya, Rammohan, Aluru, Babu, Tirumalasetty Munichandra, Zheng, Gui Yu, Chen, Weibin, Rajendra, Wudayagiri, Zyryanov, Grigory V., Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190100/
https://www.ncbi.nlm.nih.gov/pubmed/34108504
http://dx.doi.org/10.1038/s41598-021-90287-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190100/
https://www.ncbi.nlm.nih.gov/pubmed/34108504
http://dx.doi.org/10.1038/s41598-021-90287-3

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