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m6A demethylase FTO induces NELL2 expression by inhibiting E2F1 m6A modification leading to metastasis of non-small cell lung cancer

Non-small cell lung cancer (NSCLC) represents one of the primary causes of cancer-related mortality all over the world. Following our initial finding of the upregulated expression of E2F transcription factor-1 (E2F1) in the NSCLC-related microarray, this study aimed to explore the regulatory role of...

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Detalles Bibliográficos
Autores principales: Wang, Yanyun, Li, Man, Zhang, Lin, Chen, Yitong, Zhang, Shoudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190133/
https://www.ncbi.nlm.nih.gov/pubmed/34169146
http://dx.doi.org/10.1016/j.omto.2021.04.011