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Apoptotic mesenchymal stromal cells support osteoclastogenesis while inhibiting multinucleated giant cells formation in vitro
In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation. Favorable outcomes are observed despite short-term engraftments of implanted MSCs, highlighting the...
Autores principales: | Humbert, Paul, Brennan, Meadhbh Á., De Lima, Julien, Brion, Régis, Adrait, Annie, Charrier, Céline, Brulin, Bénédicte, Trichet, Valérie, Couté, Yohann, Blanchard, Frédéric, Layrolle, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190145/ https://www.ncbi.nlm.nih.gov/pubmed/34108508 http://dx.doi.org/10.1038/s41598-021-91258-4 |
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