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Studying leukemia stem cell properties and vulnerabilities with human iPSCs

The reprogramming of cancer cells into induced pluripotent stem cells (iPSCs) can capture entire cancer genomes, and thus create genetically faithful models of human cancers. By providing stringent genetically clonal conditions, iPSC modeling can also unveil non-genetic sources of cancer heterogenei...

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Detalles Bibliográficos
Autores principales: Spyrou, Nikolaos, Papapetrou, Eirini P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190184/
https://www.ncbi.nlm.nih.gov/pubmed/33388708
http://dx.doi.org/10.1016/j.scr.2020.102117

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