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Studying leukemia stem cell properties and vulnerabilities with human iPSCs
The reprogramming of cancer cells into induced pluripotent stem cells (iPSCs) can capture entire cancer genomes, and thus create genetically faithful models of human cancers. By providing stringent genetically clonal conditions, iPSC modeling can also unveil non-genetic sources of cancer heterogenei...
Autores principales: | Spyrou, Nikolaos, Papapetrou, Eirini P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190184/ https://www.ncbi.nlm.nih.gov/pubmed/33388708 http://dx.doi.org/10.1016/j.scr.2020.102117 |
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