PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer

Cancer-associated fibroblasts (CAFs) play significant roles in drug resistance through different ways. Antitumor therapies, including molecular targeted interventions, not only effect tumor cells but also modulate the phenotype and characteristics of CAFs, which can in turn blunt the therapeutic res...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaoting, Fang, Tian, Xu, Sen, Jin, Ping, Zhou, Dongchen, Wang, Zhengzheng, Li, Huayi, Yang, Zongyuan, Chen, Gang, Zheng, Xu, Xia, Yu, Wei, Xiao, Zhang, Zeyu, Yang, Xin, Wang, Ya, Gao, Qinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190269/
https://www.ncbi.nlm.nih.gov/pubmed/34108603
http://dx.doi.org/10.1038/s41698-021-00189-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190269/
https://www.ncbi.nlm.nih.gov/pubmed/34108603
http://dx.doi.org/10.1038/s41698-021-00189-w

Ejemplares similares