Cargando…
PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer
Cancer-associated fibroblasts (CAFs) play significant roles in drug resistance through different ways. Antitumor therapies, including molecular targeted interventions, not only effect tumor cells but also modulate the phenotype and characteristics of CAFs, which can in turn blunt the therapeutic res...
Autores principales: | Li, Xiaoting, Fang, Tian, Xu, Sen, Jin, Ping, Zhou, Dongchen, Wang, Zhengzheng, Li, Huayi, Yang, Zongyuan, Chen, Gang, Zheng, Xu, Xia, Yu, Wei, Xiao, Zhang, Zeyu, Yang, Xin, Wang, Ya, Gao, Qinglei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190269/ https://www.ncbi.nlm.nih.gov/pubmed/34108603 http://dx.doi.org/10.1038/s41698-021-00189-w |
Ejemplares similares
-
Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation
por: Li, Xiaoting, et al.
Publicado: (2019) -
Reprogramming of stromal fibroblasts by SNAI2 contributes to tumor desmoplasia and ovarian cancer progression
por: Yang, Zongyuan, et al.
Publicado: (2017) -
MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis
por: Yang, Zongyuan, et al.
Publicado: (2016) -
TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway
por: Wei, Xiao, et al.
Publicado: (2021) -
Effectiveness and Safety of Niraparib as Neoadjuvant Therapy in Advanced Ovarian Cancer With Homologous Recombination Deficiency (NANT): Study Protocol for a Prospective, Multicenter, Exploratory, Phase 2, Single-Arm Study
por: Zhou, Dongchen, et al.
Publicado: (2022)