WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression

WSX1, a receptor subunit for IL-27, is widely expressed in immune cells and closely involved in immune response, but its function in nonimmune cells remains unknown. Here we report that WSX1 is highly expressed in human hepatocytes but downregulated in hepatocellular carcinoma (HCC) cells. Using NRA...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Man, Xia, Xueqing, Hu, Jiemiao, Fowlkes, Natalie Wall, Li, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190270/
https://www.ncbi.nlm.nih.gov/pubmed/34108491
http://dx.doi.org/10.1038/s41467-021-23864-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190270/
https://www.ncbi.nlm.nih.gov/pubmed/34108491
http://dx.doi.org/10.1038/s41467-021-23864-9

Ejemplares similares