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Novel neutralizing human monoclonal antibodies against tetanus neurotoxin

Tetanus is a fatal disease caused by tetanus neurotoxin (TeNT). TeNT is composed of a light chain (Lc) and a heavy chain, the latter of which is classified into two domains, N-terminus Hn and C-terminus Hc. Several TeNT-neutralizing antibodies have been reported, but it remains unclear which TeNT do...

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Detalles Bibliográficos
Autores principales: Minamitani, Takeharu, Kiyose, Karin, Otsubo, Ryota, Ito, Toshihiro, Akiba, Hiroki, Furuta, Rika A., Inoue, Tsuyoshi, Tsumoto, Kouhei, Satake, Masahiro, Yasui, Teruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190289/
https://www.ncbi.nlm.nih.gov/pubmed/34108521
http://dx.doi.org/10.1038/s41598-021-91597-2