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Pregnancy-induced effects on memory B-cell development in multiple sclerosis

In MS, pathogenic memory B cells infiltrate the brain and develop into antibody-secreting cells. Chemokine receptors not only define their brain-infiltrating capacity, but also assist in their maturation in germinal centers. How this corresponds to pregnancy, as a naturally occurring modifier of MS,...

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Detalles Bibliográficos
Autores principales: Janssen, Malou, Rijvers, Liza, Koetzier, Steven C., Wierenga-Wolf, Annet F., Melief, Marie-José, van Langelaar, Jamie, Runia, Tessel F., de Groot, Christianne J. M., Neuteboom, Rinze, Smolders, Joost, van Luijn, Marvin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190290/
https://www.ncbi.nlm.nih.gov/pubmed/34108575
http://dx.doi.org/10.1038/s41598-021-91655-9