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Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1

Cas12i is a newly identified member of the functionally diverse type V CRISPR-Cas effectors. Although Cas12i has the potential to serve as genome-editing tool, its structural and functional characteristics need to be investigated in more detail before effective application. Here we report the crysta...

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Detalles Bibliográficos
Autores principales:	Zhang, Bo, Luo, Diyin, Li, Yu, Perčulija, Vanja, Chen, Jing, Lin, Jinying, Ye, Yangmiao, Ouyang, Songying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190297/ https://www.ncbi.nlm.nih.gov/pubmed/34108490 http://dx.doi.org/10.1038/s41467-021-23876-5

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