Association of Premature Immune Aging and Cytomegalovirus After Solid Organ Transplant

Immune function is altered with increasing age. Infection with cytomegalovirus (CMV) accelerates age-related immunological changes resulting in expanded oligoclonal memory CD8 T cell populations with impaired proliferation, signaling, and cytokine production. As a consequence, elderly CMV seropositi...

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Detalles Bibliográficos
Autores principales: Higdon, Lauren E., Gustafson, Claire E., Ji, Xuhuai, Sahoo, Malaya K., Pinsky, Benjamin A., Margulies, Kenneth B., Maecker, Holden T., Goronzy, Jorg, Maltzman, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190404/
https://www.ncbi.nlm.nih.gov/pubmed/34122420
http://dx.doi.org/10.3389/fimmu.2021.661551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190404/
https://www.ncbi.nlm.nih.gov/pubmed/34122420
http://dx.doi.org/10.3389/fimmu.2021.661551

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