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Co-Administration of Anticancer Candidate MK-2206 Enhances the Efficacy of BCG Vaccine Against Mycobacterium tuberculosis in Mice and Guinea Pigs

The failure of M. bovis BCG to induce long-term protection has been endowed to its inability to escape the phagolysosome, leading to mild activation of CD8(+) mediated T cell response. Induction of apoptosis in host cells plays an important role in potentiating dendritic cells-mediated priming of CD...

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Detalles Bibliográficos
Autores principales:	Bouzeyen, Rania, Chugh, Saurabh, Gosain, Tannu Priya, Barbouche, Mohamed-Ridha, Haoues, Meriam, Rao, Kanury V. S., Essafi, Makram, Singh, Ramandeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190480/ https://www.ncbi.nlm.nih.gov/pubmed/34122406 http://dx.doi.org/10.3389/fimmu.2021.645962

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