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Treatment with lentiviral vectors encoding shRNA against interleukin 10 modulates the immunosuppressive activity of murine colon carcinoma-associated myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are potent suppressors of antitumor immunity and their accumulation is often associated with poor prognosis. The aim of the present study was to determine the mechanisms of action of lentiviral vectors encoding short hairpin (sh)RNA against interleukin-10 (IL...

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Detalles Bibliográficos
Autores principales:	Anger-Góra, Natalia, Węgierek-Ciura, Katarzyna, Szczygieł, Agnieszka, Mierzejewska, Jagoda, Pajtasz-Piasecka, Elżbieta, Rossowska, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190769/ https://www.ncbi.nlm.nih.gov/pubmed/34122633 http://dx.doi.org/10.3892/ol.2021.12843

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