Cargando…

Proteomic Analysis Reveals That Metformin Suppresses PSMD2, STIP1, and CAP1 for Preventing Gastric Cancer AGS Cell Proliferation and Migration

[Image: see text] Metformin is one of the most widely used anti-diabetic drugs in type-II diabetes treatment. The mechanism of decreasing blood glucose is believed to suppress hepatic gluconeogenesis by increasing muscular glucose uptake and insulin sensitivity. Recent studies suggest that metformin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Wei-Hsuan, Chen, Szu-Kai, Huang, Hsuan-Cheng, Juan, Hsueh-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190800/ https://www.ncbi.nlm.nih.gov/pubmed/34124444 http://dx.doi.org/10.1021/acsomega.1c00894

Ejemplares similares

STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway
por: Guo, Xiangjun, et al.
Publicado: (2019)

Tumor Stress-Induced Phosphoprotein1 (STIP1) as a Prognostic Biomarker in Ovarian Cancer
por: Chao, Angel, et al.
Publicado: (2013)

Prognostic Significance of PSMD1 Expression in Patients with Gastric Cancer
por: Xiong, Wenjun, et al.
Publicado: (2019)

PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism
por: Tan, Yanjie, et al.
Publicado: (2019)

PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration
por: Zhang, Jin, et al.
Publicado: (2023)

Hsa-miR-1248 suppressed the proliferation, invasion and migration of colorectal cancer cells via inhibiting PSMD10
por: Wang, Chengxing, et al.
Publicado: (2022)

Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4
por: Jia, Changxin, et al.
Publicado: (2023)

The Expression of FOXE-1 and STIP-1 in Papillary Thyroid Carcinoma and Their Relationship with Patient Prognosis
por: M Fouad, Enas, et al.
Publicado: (2018)

Intracellular targeting of STIP1 inhibits human cancer cell line growth
por: Lin, Chiao-Yun, et al.
Publicado: (2021)

Parkinson’s Disease-Specific Autoantibodies against the Neuroprotective Co-Chaperone STIP1
por: Tan, Jolene Su Yi, et al.
Publicado: (2022)

26S Proteasome Non-ATPase Regulatory Subunits 1 (PSMD1) and 3 (PSMD3) as Putative Targets for Cancer Prognosis and Therapy
por: Rubio, Andres J., et al.
Publicado: (2021)

Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)
por: Beraldo, Flavio H., et al.
Publicado: (2015)

JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells
por: Chao, Angel, et al.
Publicado: (2022)

Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells
por: Lin, Li-Ling, et al.
Publicado: (2015)

Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B
por: Wang, Jianjiang, et al.
Publicado: (2021)

Comparative proteomics identify HSP90A, STIP1 and TAGLN-2 in serum extracellular vesicles as potential circulating biomarkers for human adenomyosis
por: Chen, Dayong, et al.
Publicado: (2022)

Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma
por: Wang, Jiang, et al.
Publicado: (2017)

Revealing the Molecular Mechanism of Gastric Cancer Marker Annexin A4 in Cancer Cell Proliferation Using Exon Arrays
por: Lin, Li-Ling, et al.
Publicado: (2012)

Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
por: Lackie, Rachel E., et al.
Publicado: (2022)

Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion
por: Zeng, Jie, et al.
Publicado: (2021)

Serum Autoantibodies against STIP1 as a Potential Biomarker in the Diagnosis of Esophageal Squamous Cell Carcinoma
por: Xu, Yi-Wei, et al.
Publicado: (2017)

Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3), play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B
por: Bencomo-Alvarez, Alfonso E., et al.
Publicado: (2021)

Regulation of Drp1 and enhancement of mitochondrial fission by the deubiquitinating enzyme PSMD14 facilitates the proliferation of bladder cancer cells
por: Song, Wei, et al.
Publicado: (2023)

Effects of STIP1 and GLCCI1 polymorphisms on the risk of childhood asthma and inhaled corticosteroid response in Chinese asthmatic children
por: Huang, Juan, et al.
Publicado: (2020)

Beyond COVID: Reframing the Global Problematique with STiP (Systems Thinking in Practice)
por: Ison, Raymond L.
Publicado: (2023)

GOLPH3 Promotes Cancer Growth by Interacting With STIP1 and Regulating Telomerase Activity in Pancreatic Ductal Adenocarcinoma
por: Wang, Kebing, et al.
Publicado: (2020)

Serum STIP1, a Novel Indicator for Microvascular Invasion, Predicts Outcomes and Treatment Response in Hepatocellular Carcinoma
por: Ma, Xiao-Lu, et al.
Publicado: (2020)

PSMD8 can serve as potential biomarker and therapeutic target of the PSMD family in ovarian cancer: based on bioinformatics analysis and in vitro validation
por: Li, Xiao, et al.
Publicado: (2023)

STIP1/HOP Regulates the Actin Cytoskeleton through Interactions with Actin and Changes in Actin-Binding Proteins Cofilin and Profilin
por: Beckley, Samantha Joy, et al.
Publicado: (2020)

Psychometric evaluation of the Estonian version of the Semi-structured Interview for Personality Functioning DSM-5 (STiP-5.1)
por: Oitsalu, Maarja-Liisa, et al.
Publicado: (2022)

Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy
por: Adler, Julia, et al.
Publicado: (2023)

miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10
por: Liu, Fangzhou, et al.
Publicado: (2018)

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
por: Bhattacharya, Kaushik, et al.
Publicado: (2020)

PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway
por: Xu, Xinchun, et al.
Publicado: (2021)

PSMD9 expression predicts radiotherapy response in breast cancer
por: Langlands, Fiona E, et al.
Publicado: (2014)

Upregulation of PSMD4 gene by hypoxia in prostate cancer cells
por: AYDOĞAN TÜRKOĞLU, Sümeyye, et al.
Publicado: (2020)

Prognostic Implication and Immunological Role of PSMD2 in Lung Adenocarcinoma
por: Zhao, Huihui, et al.
Publicado: (2022)

Haploinsufficiency of PSMD12 Causes Proteasome Dysfunction and Subclinical Autoinflammation
por: Yan, Kai, et al.
Publicado: (2022)

Persistence and Use of Ixekizumab in Patients with Psoriatic Arthritis in Real-World Practice in Spain. The PRO-STIP Study
por: Joven, Beatriz, et al.
Publicado: (2023)

Analysis and experimental validation of the innate immune gene PSMD1 in liver hepatocellular carcinoma and pan-cancer
por: Chen, Xing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7bfec2fkkpd4prvc34qg6v482s