Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer

Antibody-recruiting molecules (ARMs) are one of the most promising tools to redirect the immune response towards cancer cells. In this review, we aim to highlight the recent advances in the field. We will illustrate the advantages of different ARM approaches and emphasize the importance of a multiva...

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Detalles Bibliográficos
Autores principales: Achilli, Silvia, Berthet, Nathalie, Renaudet, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190906/
https://www.ncbi.nlm.nih.gov/pubmed/34212148
http://dx.doi.org/10.1039/d1cb00007a
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author Achilli, Silvia
Berthet, Nathalie
Renaudet, Olivier
author_facet Achilli, Silvia
Berthet, Nathalie
Renaudet, Olivier
author_sort Achilli, Silvia
collection PubMed
description Antibody-recruiting molecules (ARMs) are one of the most promising tools to redirect the immune response towards cancer cells. In this review, we aim to highlight the recent advances in the field. We will illustrate the advantages of different ARM approaches and emphasize the importance of a multivalent presentation of the binding units.
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spelling pubmed-81909062021-06-29 Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer Achilli, Silvia Berthet, Nathalie Renaudet, Olivier RSC Chem Biol Chemistry Antibody-recruiting molecules (ARMs) are one of the most promising tools to redirect the immune response towards cancer cells. In this review, we aim to highlight the recent advances in the field. We will illustrate the advantages of different ARM approaches and emphasize the importance of a multivalent presentation of the binding units. RSC 2021-03-04 /pmc/articles/PMC8190906/ /pubmed/34212148 http://dx.doi.org/10.1039/d1cb00007a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Achilli, Silvia
Berthet, Nathalie
Renaudet, Olivier
Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title_full Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title_fullStr Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title_full_unstemmed Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title_short Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
title_sort antibody recruiting molecules (arms): synthetic immunotherapeutics to fight cancer
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190906/
https://www.ncbi.nlm.nih.gov/pubmed/34212148
http://dx.doi.org/10.1039/d1cb00007a
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