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Bioorthogonal protein labelling enables the study of antigen processing of citrullinated and carbamylated auto-antigens
Proteolysis is fundamental to many biological processes. In the immune system, it underpins the activation of the adaptive immune response: degradation of antigenic material into short peptides and presentation thereof on major histocompatibility complexes, leads to activation of T-cells. This initi...
Autores principales: | van Leeuwen, Tyrza, Araman, Can, Pieper Pournara, Linda, Kampstra, Arieke S. B., Bakkum, Thomas, Marqvorsen, Mikkel H. S., Nascimento, Clarissa R., Groenewold, G. J. Mirjam, van der Wulp, Willemijn, Camps, Marcel G. M., Janssen, George M. C., van Veelen, Peter A., van Westen, Gerard J. P., Janssen, Antonius P. A., Florea, Bogdan I., Overkleeft, Herman S., Ossendorp, Ferry A., Toes, René E. M., van Kasteren, Sander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190914/ https://www.ncbi.nlm.nih.gov/pubmed/34212151 http://dx.doi.org/10.1039/d1cb00009h |
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