Cargando…

Combination of UPLC–Q-TOF/MS and Network Pharmacology to Reveal the Mechanism of Qizhen Decoction in the Treatment of Colon Cancer

[Image: see text] Traditional Chinese medicine (TCM) has been utilized for the treatment of colon cancer. Qizhen decoction (QZD), a potential compound prescription of TCM, possesses multiple biological activities. It has been proven clinically effective in the treatment of colon cancer. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Xianbin, Liu, Chuanxin, Lu, Peng, Guo, Yuzhu, Zhao, Chenchen, Yang, Yuying, Bo, Zhichao, Wang, Fangyuan, Peng, Yingying, Meng, Jingyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190929/ https://www.ncbi.nlm.nih.gov/pubmed/34124457 http://dx.doi.org/10.1021/acsomega.1c01183

Ejemplares similares

Metabolomics Study of Shaoyao Plants Decoction on the Proximal and Distal Colon in Mice with Dextran Sulfate Sodium-Induced Colitis by UPLC-Q-TOF-MS
por: Luo, Yiting, et al.
Publicado: (2022)

Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
por: Shen, Zhuo Jun, et al.
Publicado: (2022)

Serum Pharmacochemistry Analysis Using UPLC-Q-TOF/MS after Oral Administration to Rats of Shenfu Decoction
por: He, Jia-le, et al.
Publicado: (2015)

Identification of prototype compounds and their metabolites in rats’ serum from Xuefu Zhuyu Decoction by UPLC-Q-TOF/MS
por: Zhang, Xiaoyu, et al.
Publicado: (2022)

Plasma metabolic profiling analysis of Cortex Periplocae-induced cardiotoxicity based on UPLC/Q-TOF-MS
por: Li, Yubo, et al.
Publicado: (2018)

A combination of PD-1/PD-L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy
por: Kong, Xianbin, et al.
Publicado: (2021)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Exploring potential mechanism of ciwujia tablets for insomnia by UPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
por: Liu, Hongda, et al.
Publicado: (2022)

High-Throughput Untargeted Serum Metabolomics Analysis of Hyperuricemia Patients by UPLC-Q-TOF/MS
por: Qin, Nankun, et al.
Publicado: (2021)

Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
por: Bai, Yue, et al.
Publicado: (2019)

Rapid identification of chemical profile in Gandou decoction by UPLC-Q-TOF-MS(E) coupled with novel informatics UNIFI platform
por: Xu, Li, et al.
Publicado: (2020)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of Coreopsis tinctoria Nutt.
por: Liu, Jing, et al.
Publicado: (2022)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Based on UPLC-Q-TOF-MS/MS, Systematic Network Pharmacology, and Molecular Docking to Explore the Potential Mechanism of Fructus Aurantii for Major Depression Disorder
por: Xie, Yating, et al.
Publicado: (2021)

Identification of Antitumor Active Constituents in Polygonatum sibiricum Flower by UPLC-Q-TOF-MS(E) and Network Pharmacology
por: Huang, Zhuang-zhuang, et al.
Publicado: (2020)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

Effect of Wuzi Yanzong prescription on oligoasthenozoospermia rats based on UPLC-Q-TOF-MS metabolomics
por: Chen, Zhimin, et al.
Publicado: (2022)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

The Effect of Temperature on Pressurised Hot Water Extraction of Pharmacologically Important Metabolites as Analysed by UPLC-qTOF-MS and PCA
por: Khoza, B. S., et al.
Publicado: (2014)

Unveiling the Pharmacological Mechanisms of Eleutheroside E Against Postmenopausal Osteoporosis Through UPLC-Q/TOF-MS-Based Metabolomics
por: Ma, Yong-Sheng, et al.
Publicado: (2020)

Identification of chemical components and rat serum metabolites in Danggui Buxue decoction based on UPLC-Q-TOF-MS, the UNIFI platform and molecular networks
por: Lv, Yanhui, et al.
Publicado: (2023)

NLRP3 inflammasome and lipid metabolism analysis based on UPLC-Q-TOF-MS in gouty nephropathy
por: Zhang, Yan-Zi, et al.
Publicado: (2019)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Study on the mechanism of acute liver injury protection in Rhubarb anthraquinone by metabolomics based on UPLC-Q-TOF-MS
por: Gong, Xiaohong, et al.
Publicado: (2023)

Systematically characterize the substance basis of Jinzhen oral liquid and their pharmacological mechanism using UPLC-Q-TOF/MS combined with network pharmacology analysis
por: Guo, Jing-Yan, et al.
Publicado: (2019)

Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsule by UPLC–Q–TOF–MS/MS
por: Zhong, Xunlong, et al.
Publicado: (2011)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

Comprehensive metabolomics study on the pathogenesis of anaplastic astrocytoma via UPLC-Q/TOF-MS
por: Du, Chao, et al.
Publicado: (2022)

Uncovering the Key Targets and Therapeutic Mechanisms of Qizhen Capsule in Gastric Cancer through Network Pharmacology and Bioinformatic Analyses
por: Zhou, Wanmei, et al.
Publicado: (2022)

DPPH Radical Scavenging and Postprandial Hyperglycemia Inhibition Activities and Flavonoid Composition Analysis of Hawk Tea by UPLC-DAD and UPLC-Q/TOF MS(E)
por: Xiao, Xuan, et al.
Publicado: (2017)

UPLC/Q-TOF MS-Based Urine Metabonomics Study to Identify Diffuse Axonal Injury Biomarkers in Rat
por: Zhang, Peng, et al.
Publicado: (2022)

Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MS(E)
por: Zhao, Yifan, et al.
Publicado: (2021)

Secondary Metabolite Profiling of Curcuma Species Grown at Different Locations Using GC/TOF and UPLC/Q-TOF MS
por: Lee, Jueun, et al.
Publicado: (2014)

Systematic characterization of metabolic profiles of ingenol in rats by UPLC-Q/TOF-MS and NMR in combination with microbial biotransformation
por: Xiao, Si-Jia, et al.
Publicado: (2021)

Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS
por: Wang, Shiqiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0feujiucppp4i0dea657usibs1