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Constraining PERMANOVA and LDM to within-set comparisons by projection improves the efficiency of analyses of matched sets of microbiome data

BACKGROUND: Matched-set data arise frequently in microbiome studies. For example, we may collect pre- and post-treatment samples from a set of individuals, or use important confounding variables to match data from case participants to one or more control participants. Thus, there is a need for stati...

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Detalles Bibliográficos
Autores principales: Zhu, Zhengyi, Satten, Glen A., Mitchell, Caroline, Hu, Yi-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191060/
https://www.ncbi.nlm.nih.gov/pubmed/34108046
http://dx.doi.org/10.1186/s40168-021-01034-9

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