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Blocking siglec-10(hi) tumor-associated macrophages improves anti-tumor immunity and enhances immunotherapy for hepatocellular carcinoma
BACKGROUND: Tumor-associated macrophages (TAMs) promote key processes in the modulation of tumor microenvironment (TME). However, the clinical significance of heterogeneous subpopulations of TAMs in hepatocellular carcinoma (HCC) remains unknown. METHODS: HCC tissues from Zhongshan Hospital and data...
Autores principales: | Xiao, Nan, Zhu, Xiaodong, Li, Kangshuai, Chen, Yifan, Liu, Xuefeng, Xu, Bin, Lei, Ming, Xu, Jiejie, Sun, Hui-Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191104/ https://www.ncbi.nlm.nih.gov/pubmed/34112250 http://dx.doi.org/10.1186/s40164-021-00230-5 |
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