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Constrained transformer network for ECG signal processing and arrhythmia classification

BACKGROUND: Heart disease diagnosis is a challenging task and it is important to explore useful information from the massive amount of electrocardiogram (ECG) records of patients. The high-precision diagnostic identification of ECG can save clinicians and cardiologists considerable time while helpin...

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Autores principales: Che, Chao, Zhang, Peiliang, Zhu, Min, Qu, Yue, Jin, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191107/
https://www.ncbi.nlm.nih.gov/pubmed/34107920
http://dx.doi.org/10.1186/s12911-021-01546-2
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author Che, Chao
Zhang, Peiliang
Zhu, Min
Qu, Yue
Jin, Bo
author_facet Che, Chao
Zhang, Peiliang
Zhu, Min
Qu, Yue
Jin, Bo
author_sort Che, Chao
collection PubMed
description BACKGROUND: Heart disease diagnosis is a challenging task and it is important to explore useful information from the massive amount of electrocardiogram (ECG) records of patients. The high-precision diagnostic identification of ECG can save clinicians and cardiologists considerable time while helping reduce the possibility of misdiagnosis at the same time.Currently, some deep learning-based methods can effectively perform feature selection and classification prediction, reducing the consumption of manpower. METHODS: In this work, an end-to-end deep learning framework based on convolutional neural network (CNN) is proposed for ECG signal processing and arrhythmia classification. In the framework, a transformer network is embedded in CNN to capture the temporal information of ECG signals and a new link constraint is introduced to the loss function to enhance the classification ability of the embedding vector. RESULTS: To evaluate the proposed method, extensive experiments based on real-world data were conducted. Experimental results show that the proposed model achieve better performance than most baselines. The experiment results also proved that the transformer network pays more attention to the temporal continuity of the data and captures the hidden deep features of the data well. The link constraint strengthens the constraint on the embedded features and effectively suppresses the effect of data imbalance on the results. CONCLUSIONS: In this paper, an end-to-end model is used to process ECG signal and classify arrhythmia. The model combine CNN and Transformer network to extract temporal information in ECG signal and is capable of performing arrhythmia classification with acceptable accuracy. The model can help cardiologists perform assisted diagnosis of heart disease and improve the efficiency of healthcare delivery.
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spelling pubmed-81911072021-06-10 Constrained transformer network for ECG signal processing and arrhythmia classification Che, Chao Zhang, Peiliang Zhu, Min Qu, Yue Jin, Bo BMC Med Inform Decis Mak Research BACKGROUND: Heart disease diagnosis is a challenging task and it is important to explore useful information from the massive amount of electrocardiogram (ECG) records of patients. The high-precision diagnostic identification of ECG can save clinicians and cardiologists considerable time while helping reduce the possibility of misdiagnosis at the same time.Currently, some deep learning-based methods can effectively perform feature selection and classification prediction, reducing the consumption of manpower. METHODS: In this work, an end-to-end deep learning framework based on convolutional neural network (CNN) is proposed for ECG signal processing and arrhythmia classification. In the framework, a transformer network is embedded in CNN to capture the temporal information of ECG signals and a new link constraint is introduced to the loss function to enhance the classification ability of the embedding vector. RESULTS: To evaluate the proposed method, extensive experiments based on real-world data were conducted. Experimental results show that the proposed model achieve better performance than most baselines. The experiment results also proved that the transformer network pays more attention to the temporal continuity of the data and captures the hidden deep features of the data well. The link constraint strengthens the constraint on the embedded features and effectively suppresses the effect of data imbalance on the results. CONCLUSIONS: In this paper, an end-to-end model is used to process ECG signal and classify arrhythmia. The model combine CNN and Transformer network to extract temporal information in ECG signal and is capable of performing arrhythmia classification with acceptable accuracy. The model can help cardiologists perform assisted diagnosis of heart disease and improve the efficiency of healthcare delivery. BioMed Central 2021-06-09 /pmc/articles/PMC8191107/ /pubmed/34107920 http://dx.doi.org/10.1186/s12911-021-01546-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Che, Chao
Zhang, Peiliang
Zhu, Min
Qu, Yue
Jin, Bo
Constrained transformer network for ECG signal processing and arrhythmia classification
title Constrained transformer network for ECG signal processing and arrhythmia classification
title_full Constrained transformer network for ECG signal processing and arrhythmia classification
title_fullStr Constrained transformer network for ECG signal processing and arrhythmia classification
title_full_unstemmed Constrained transformer network for ECG signal processing and arrhythmia classification
title_short Constrained transformer network for ECG signal processing and arrhythmia classification
title_sort constrained transformer network for ecg signal processing and arrhythmia classification
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191107/
https://www.ncbi.nlm.nih.gov/pubmed/34107920
http://dx.doi.org/10.1186/s12911-021-01546-2
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