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Duloxetine versus ‘active’ placebo, placebo or no intervention for major depressive disorder; a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

BACKGROUND: Major depression significantly impairs quality of life, increases the risk of suicide, and poses tremendous economic burden on individuals and societies. Duloxetine, a serotonin norepinephrine reuptake inhibitor, is a widely prescribed antidepressant. The effects of duloxetine have, howe...

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Detalles Bibliográficos
Autores principales: Siddiqui, Faiza, Barbateskovic, Marija, Juul, Sophie, Katakam, Kiran Kumar, Munkholm, Klaus, Gluud, Christian, Jakobsen, Janus Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191126/
https://www.ncbi.nlm.nih.gov/pubmed/34108032
http://dx.doi.org/10.1186/s13643-021-01722-5