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The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

BACKGROUND: The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or regeneration. Wnt/beta-Catenin signaling functions as a primary cue controlling this process, but how Wnt ligand activity is locally restric...

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Detalles Bibliográficos
Autores principales: Ziegler, Berenice, Yiallouros, Irene, Trageser, Benjamin, Kumar, Sumit, Mercker, Moritz, Kling, Svenja, Fath, Maike, Warnken, Uwe, Schnölzer, Martina, Holstein, Thomas W., Hartl, Markus, Marciniak-Czochra, Anna, Stetefeld, Jörg, Stöcker, Walter, Özbek, Suat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191133/
https://www.ncbi.nlm.nih.gov/pubmed/34107975
http://dx.doi.org/10.1186/s12915-021-01046-9