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Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19

BACKGROUND: Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-COV-2). Many aspects of its pathology and pathogenesis are not well understood. MATERIAL AND METHODS: We describe a series of spontaneous air leak cases we found in our...

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Autores principales: Wadhawa, Reema, Thakkar, Avani, Chhanwal, Heena Sunil, Bhalotra, Anju, Rana, Yashpal, Wadhawa, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191243/
https://www.ncbi.nlm.nih.gov/pubmed/34188623
http://dx.doi.org/10.4103/sja.sja_939_20
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author Wadhawa, Reema
Thakkar, Avani
Chhanwal, Heena Sunil
Bhalotra, Anju
Rana, Yashpal
Wadhawa, Vivek
author_facet Wadhawa, Reema
Thakkar, Avani
Chhanwal, Heena Sunil
Bhalotra, Anju
Rana, Yashpal
Wadhawa, Vivek
author_sort Wadhawa, Reema
collection PubMed
description BACKGROUND: Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-COV-2). Many aspects of its pathology and pathogenesis are not well understood. MATERIAL AND METHODS: We describe a series of spontaneous air leak cases we found in our coronavirus disease 2019 (COVID-19) positive 1086-patient cohort. RESULTS: Two out of six patients eventually required mechanical ventilation and succumbed to COVID-19. We presume that acute lung injury leading to SARS-CoV-2 with associated acute respiratory distress syndrome predisposes patients to this complication. CONCLUSION: This series is presented to highlight the emerging association of COVID-19 with spontaneous air leaks leading to pneumomediastinum, pneumothorax, and subsequent subcutaneous emphysema even in patients who have never received invasive mechanical ventilation and this may be more likely with the institution of high flow nasal cannula.
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spelling pubmed-81912432021-06-28 Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19 Wadhawa, Reema Thakkar, Avani Chhanwal, Heena Sunil Bhalotra, Anju Rana, Yashpal Wadhawa, Vivek Saudi J Anaesth Original Article BACKGROUND: Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-COV-2). Many aspects of its pathology and pathogenesis are not well understood. MATERIAL AND METHODS: We describe a series of spontaneous air leak cases we found in our coronavirus disease 2019 (COVID-19) positive 1086-patient cohort. RESULTS: Two out of six patients eventually required mechanical ventilation and succumbed to COVID-19. We presume that acute lung injury leading to SARS-CoV-2 with associated acute respiratory distress syndrome predisposes patients to this complication. CONCLUSION: This series is presented to highlight the emerging association of COVID-19 with spontaneous air leaks leading to pneumomediastinum, pneumothorax, and subsequent subcutaneous emphysema even in patients who have never received invasive mechanical ventilation and this may be more likely with the institution of high flow nasal cannula. Wolters Kluwer - Medknow 2021 2021-04-01 /pmc/articles/PMC8191243/ /pubmed/34188623 http://dx.doi.org/10.4103/sja.sja_939_20 Text en Copyright: © 2021 Saudi Journal of Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Wadhawa, Reema
Thakkar, Avani
Chhanwal, Heena Sunil
Bhalotra, Anju
Rana, Yashpal
Wadhawa, Vivek
Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title_full Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title_fullStr Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title_full_unstemmed Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title_short Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19
title_sort spontaneous pneumomediastinum and subcutaneous emphysema in patients with covid-19
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191243/
https://www.ncbi.nlm.nih.gov/pubmed/34188623
http://dx.doi.org/10.4103/sja.sja_939_20
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