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Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy

Macroautophagy (hereafter, autophagy) is a process that directs the degradation of cytoplasmic material in lysosomes. In addition to its homeostatic roles, autophagy undergoes dynamic positive and negative regulation in response to multiple forms of cellular stress, thus enabling the survival of cel...

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Detalles Bibliográficos
Autores principales:	Mimura, Kaito, Sakamaki, Jun-Ichi, Morishita, Hideaki, Kawazu, Masahito, Mano, Hiroyuki, Mizushima, Noboru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191307/ https://www.ncbi.nlm.nih.gov/pubmed/34000301 http://dx.doi.org/10.1016/j.jbc.2021.100780

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