Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs

The adhesion G protein–coupled receptor CD97 and its ligand complement decay-accelerating factor CD55 are important binding partners in the human immune system. Dysfunction in this binding has been linked to immune disorders such as multiple sclerosis and rheumatoid arthritis, as well as various can...

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Detalles Bibliográficos
Autores principales: Niu, Minghui, Xu, Shengzhao, Yang, Jie, Yao, Deqiang, Li, Na, Yan, Jie, Zhong, Guisheng, Song, Gaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191316/
https://www.ncbi.nlm.nih.gov/pubmed/33992645
http://dx.doi.org/10.1016/j.jbc.2021.100776

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