Cargando…

Speeding Up the Heart? Traditional and New Perspectives on HCN4 Function

The sinoatrial node (SAN) is the primary pacemaker of the heart and is responsible for generating the intrinsic heartbeat. Within the SAN, spontaneously active pacemaker cells initiate the electrical activity that causes the contraction of all cardiomyocytes. The firing rate of pacemaker cells depen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hennis, Konstantin, Rötzer, René D., Piantoni, Chiara, Biel, Martin, Wahl-Schott, Christian, Fenske, Stefanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191466/ https://www.ncbi.nlm.nih.gov/pubmed/34122140 http://dx.doi.org/10.3389/fphys.2021.669029

Ejemplares similares

Paradigm shift: new concepts for HCN4 function in cardiac pacemaking
por: Hennis, Konstantin, et al.
Publicado: (2022)

cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
por: Fenske, Stefanie, et al.
Publicado: (2020)

Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice
por: Stieglitz, Marc S., et al.
Publicado: (2018)

The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores
por: Zong, Xiangang, et al.
Publicado: (2009)

Two HCN4 Channels Play Functional Roles in the Zebrafish Heart
por: Liu, Jiaying, et al.
Publicado: (2022)

Regulation of HCN Channels by Protein Interactions
por: Peters, Colin H., et al.
Publicado: (2022)

cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4
por: Porro, Alessandro, et al.
Publicado: (2020)

Regulation of HCN2 Current by PI3K/Akt Signaling
por: Lu, Zhongju, et al.
Publicado: (2020)

Palmitoylation regulates the magnitude of HCN4-mediated currents in mammalian cells
por: Congreve, Samitha Dilini, et al.
Publicado: (2023)

Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1
por: Végh, Anna M. D., et al.
Publicado: (2021)

Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts
por: Yüksel, Sezin, et al.
Publicado: (2022)

A gene therapy for inherited blindness using dCas9-VPR–mediated transcriptional activation
por: Böhm, Sybille, et al.
Publicado: (2020)

Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models
por: Bucchi, Annalisa, et al.
Publicado: (2012)

HCN Channels and Heart Rate
por: Scicchitano, Pietro, et al.
Publicado: (2012)

Review: HCN Channels in the Heart
por: Depuydt, Anne-Sophie, et al.
Publicado: (2022)

Probing the bradycardic drug binding receptor of HCN-encoded pacemaker channels
por: Chan, Yau-Chi, et al.
Publicado: (2009)

Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements
por: Saponaro, Andrea, et al.
Publicado: (2022)

Editorial: Women in Cardiac Electrophysiology: 2022
por: Meo, Marianna, et al.
Publicado: (2023)

Corrigendum: Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements
por: Saponaro, Andrea, et al.
Publicado: (2023)

Hyperpolarization-Activated Cyclic Nucleotide-Gated Non-selective (HCN) Ion Channels Regulate Human and Murine Urinary Bladder Contractility
por: Mader, Felix, et al.
Publicado: (2018)

Salts of HCN‐Cyanide Aggregates: [CN(HCN)(2)](−) and [CN(HCN)(3)](−)
por: Bläsing, Kevin, et al.
Publicado: (2020)

The impact of HCN4 channels on CNS brain networks as a new target in pain development
por: Häfele, Maximilian, et al.
Publicado: (2023)

Effectiveness of Traditional Strength vs. Power Training on Muscle Strength, Power and Speed with Youth: A Systematic Review and Meta-Analysis
por: Behm, David G., et al.
Publicado: (2017)

The influence of age and sex on speed–strength performance in children between 10 and 14 years of age
por: Warneke, Konstantin, et al.
Publicado: (2023)

The cGMP-Dependent Protein Kinase II Is an Inhibitory Modulator of the Hyperpolarization-Activated HCN2 Channel
por: Hammelmann, Verena, et al.
Publicado: (2011)

Combining Chronic Ischemic Preconditioning and Inspiratory Muscle Warm-Up to Enhance On-Ice Time-Trial Performance in Elite Speed Skaters
por: Richard, Philippe, et al.
Publicado: (2018)

HCN1 Channels Enhance Rod System Responsivity in the Retina under Conditions of Light Exposure
por: Sothilingam, Vithiyanjali, et al.
Publicado: (2016)

An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities
por: Wemhöner, Konstantin, et al.
Publicado: (2015)

Heart Rate Variability – A Historical Perspective
por: Billman, George E.
Publicado: (2011)

Heart Rate Behavior in Speed Climbing
por: Fuss, Franz Konstantin, et al.
Publicado: (2020)

HCN channels sense temperature and determine heart rate responses to heat
por: Wu, Yuejin, et al.
Publicado: (2023)

Mitochondrial Dynamics and the ER: The Plant Perspective
por: Mueller, Stefanie J., et al.
Publicado: (2015)

Effects of bright light treatment on psychomotor speed in athletes
por: Tulppo, Mikko P., et al.
Publicado: (2014)

Autonomic Control of the Heart and Its Clinical Impact. A Personal Perspective
por: La Rovere, Maria Teresa, et al.
Publicado: (2020)

Caffeine and Bicarbonate for Speed. A Meta-Analysis of Legal Supplements Potential for Improving Intense Endurance Exercise Performance
por: Christensen, Peter M., et al.
Publicado: (2017)

Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function
por: Grimm, Christian, et al.
Publicado: (2017)

The protein interaction networks of mucolipins and two-pore channels
por: Krogsaeter, Einar K., et al.
Publicado: (2019)

ACTN3: More than Just a Gene for Speed
por: Pickering, Craig, et al.
Publicado: (2017)

Combined Plyometric and Short Sprint Training in U-15 Male Soccer Players: Effects on Measures of Jump, Speed, Change of Direction, Repeated Sprint, and Balance
por: Aloui, Ghaith, et al.
Publicado: (2022)

Heart Rate Asymmetry Analysis During Head-Up Tilt Test in Healthy Men
por: Pawłowski, Rafał, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_23eodnnvmdfjgidf5hk6hhqpl1