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Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report

Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history...

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Autores principales: Bhansali, Sonal Priya, Tiwari, Anjali Dave, Mittal, Sankalp, Pareek, Sitaram, Nasir, Iram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191566/
https://www.ncbi.nlm.nih.gov/pubmed/34188414
http://dx.doi.org/10.4103/njms.NJMS_52_19
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author Bhansali, Sonal Priya
Tiwari, Anjali Dave
Mittal, Sankalp
Pareek, Sitaram
Nasir, Iram
author_facet Bhansali, Sonal Priya
Tiwari, Anjali Dave
Mittal, Sankalp
Pareek, Sitaram
Nasir, Iram
author_sort Bhansali, Sonal Priya
collection PubMed
description Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history and clinicoradiological findings, FOP should be diagnosed as early as possible and noninvasively. The hallmark of diagnosis of FOP is bilateral great toe anomaly present from birth. Misdiagnosis may lead to inadvertent managements, such as manipulations, biopsies, and surgery. Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. FOP may be precipitated due to trauma to muscle. In masticatory muscle, it mainly affects masseter muscle and presents with symptom of trismus. Herein, we present a case of FOP which presented to us with trismus after wooden thorn injury and immobility of the left leg. This article also emphasize on diagnosis, precaution, and treatment of disease.
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spelling pubmed-81915662021-06-28 Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report Bhansali, Sonal Priya Tiwari, Anjali Dave Mittal, Sankalp Pareek, Sitaram Nasir, Iram Natl J Maxillofac Surg Case Report Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history and clinicoradiological findings, FOP should be diagnosed as early as possible and noninvasively. The hallmark of diagnosis of FOP is bilateral great toe anomaly present from birth. Misdiagnosis may lead to inadvertent managements, such as manipulations, biopsies, and surgery. Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. FOP may be precipitated due to trauma to muscle. In masticatory muscle, it mainly affects masseter muscle and presents with symptom of trismus. Herein, we present a case of FOP which presented to us with trismus after wooden thorn injury and immobility of the left leg. This article also emphasize on diagnosis, precaution, and treatment of disease. Wolters Kluwer - Medknow 2021 2021-03-16 /pmc/articles/PMC8191566/ /pubmed/34188414 http://dx.doi.org/10.4103/njms.NJMS_52_19 Text en Copyright: © 2021 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bhansali, Sonal Priya
Tiwari, Anjali Dave
Mittal, Sankalp
Pareek, Sitaram
Nasir, Iram
Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title_full Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title_fullStr Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title_full_unstemmed Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title_short Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
title_sort fibrodysplasia ossificans progressiva or munchmeyer's disease: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191566/
https://www.ncbi.nlm.nih.gov/pubmed/34188414
http://dx.doi.org/10.4103/njms.NJMS_52_19
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