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Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191566/ https://www.ncbi.nlm.nih.gov/pubmed/34188414 http://dx.doi.org/10.4103/njms.NJMS_52_19 |
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author | Bhansali, Sonal Priya Tiwari, Anjali Dave Mittal, Sankalp Pareek, Sitaram Nasir, Iram |
author_facet | Bhansali, Sonal Priya Tiwari, Anjali Dave Mittal, Sankalp Pareek, Sitaram Nasir, Iram |
author_sort | Bhansali, Sonal Priya |
collection | PubMed |
description | Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history and clinicoradiological findings, FOP should be diagnosed as early as possible and noninvasively. The hallmark of diagnosis of FOP is bilateral great toe anomaly present from birth. Misdiagnosis may lead to inadvertent managements, such as manipulations, biopsies, and surgery. Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. FOP may be precipitated due to trauma to muscle. In masticatory muscle, it mainly affects masseter muscle and presents with symptom of trismus. Herein, we present a case of FOP which presented to us with trismus after wooden thorn injury and immobility of the left leg. This article also emphasize on diagnosis, precaution, and treatment of disease. |
format | Online Article Text |
id | pubmed-8191566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-81915662021-06-28 Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report Bhansali, Sonal Priya Tiwari, Anjali Dave Mittal, Sankalp Pareek, Sitaram Nasir, Iram Natl J Maxillofac Surg Case Report Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease. It is characterized by widespread soft tissue ossification and congenital stigmata of the extremities, affecting all ethnic backgrounds. The worldwide reported prevalence is approximately 1/2,000,000. Based on history and clinicoradiological findings, FOP should be diagnosed as early as possible and noninvasively. The hallmark of diagnosis of FOP is bilateral great toe anomaly present from birth. Misdiagnosis may lead to inadvertent managements, such as manipulations, biopsies, and surgery. Surgery, till now, does not seem to have any role in the management of this condition and may lead to further trauma and disease progression. FOP may be precipitated due to trauma to muscle. In masticatory muscle, it mainly affects masseter muscle and presents with symptom of trismus. Herein, we present a case of FOP which presented to us with trismus after wooden thorn injury and immobility of the left leg. This article also emphasize on diagnosis, precaution, and treatment of disease. Wolters Kluwer - Medknow 2021 2021-03-16 /pmc/articles/PMC8191566/ /pubmed/34188414 http://dx.doi.org/10.4103/njms.NJMS_52_19 Text en Copyright: © 2021 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Bhansali, Sonal Priya Tiwari, Anjali Dave Mittal, Sankalp Pareek, Sitaram Nasir, Iram Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title | Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title_full | Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title_fullStr | Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title_full_unstemmed | Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title_short | Fibrodysplasia ossificans progressiva or Munchmeyer's disease: A rare case report |
title_sort | fibrodysplasia ossificans progressiva or munchmeyer's disease: a rare case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191566/ https://www.ncbi.nlm.nih.gov/pubmed/34188414 http://dx.doi.org/10.4103/njms.NJMS_52_19 |
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