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Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome

Lithium is frequently used in the treatment of bipolar disorders and is known to induce ECG alterations. This case study describes various patterns of lithium-induced ECG modifications in a patient with acute-on-chronic lithium intoxication. Clinicians should be familiar with this problem as it can...

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Autores principales: Diserens, Léonard, Porretta, Alessandra Pia, Trana, Catalina, Meier, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191624/
https://www.ncbi.nlm.nih.gov/pubmed/34108154
http://dx.doi.org/10.1136/bcr-2021-241555
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author Diserens, Léonard
Porretta, Alessandra Pia
Trana, Catalina
Meier, David
author_facet Diserens, Léonard
Porretta, Alessandra Pia
Trana, Catalina
Meier, David
author_sort Diserens, Léonard
collection PubMed
description Lithium is frequently used in the treatment of bipolar disorders and is known to induce ECG alterations. This case study describes various patterns of lithium-induced ECG modifications in a patient with acute-on-chronic lithium intoxication. Clinicians should be familiar with this problem as it can have life-threatening consequences and lead to important changes in patient’s management. Our patient was admitted for acute delirium with an ECG showing atrial fibrillation with wide QRS and ST-segment elevation. These modifications were first mistaken for an acute myocardial infarction and a diagnosis of Brugada syndrome was finally reached. Treatment after the acute phase implied changes in the therapeutic modality and required frequent monitoring.
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spelling pubmed-81916242021-06-25 Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome Diserens, Léonard Porretta, Alessandra Pia Trana, Catalina Meier, David BMJ Case Rep Case Report Lithium is frequently used in the treatment of bipolar disorders and is known to induce ECG alterations. This case study describes various patterns of lithium-induced ECG modifications in a patient with acute-on-chronic lithium intoxication. Clinicians should be familiar with this problem as it can have life-threatening consequences and lead to important changes in patient’s management. Our patient was admitted for acute delirium with an ECG showing atrial fibrillation with wide QRS and ST-segment elevation. These modifications were first mistaken for an acute myocardial infarction and a diagnosis of Brugada syndrome was finally reached. Treatment after the acute phase implied changes in the therapeutic modality and required frequent monitoring. BMJ Publishing Group 2021-06-09 /pmc/articles/PMC8191624/ /pubmed/34108154 http://dx.doi.org/10.1136/bcr-2021-241555 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Report
Diserens, Léonard
Porretta, Alessandra Pia
Trana, Catalina
Meier, David
Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title_full Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title_fullStr Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title_full_unstemmed Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title_short Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome
title_sort lithium-induced ecg modifications: navigating from acute coronary syndrome to brugada syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191624/
https://www.ncbi.nlm.nih.gov/pubmed/34108154
http://dx.doi.org/10.1136/bcr-2021-241555
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