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Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set

OBJECTIVE: Tourniquet use in total knee replacement (TKR) is believed to improve the bone-cement interface by reducing bleeding, potentially prolonging implant survival. This study aimed to compare the risk of revision for primary cemented TKR performed with or without a tourniquet. DESIGN: We analy...

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Autores principales: Farhan-Alanie, Muhamed M, Lee, Yujin, Underwood, Martin, Metcalfe, Andrew, Wilkinson, Mark J, Price, Andrew James, Warwick, Jane, Wall, Peter David Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191625/
https://www.ncbi.nlm.nih.gov/pubmed/34108163
http://dx.doi.org/10.1136/bmjopen-2020-045353
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author Farhan-Alanie, Muhamed M
Lee, Yujin
Underwood, Martin
Metcalfe, Andrew
Wilkinson, Mark J
Price, Andrew James
Warwick, Jane
Wall, Peter David Henry
author_facet Farhan-Alanie, Muhamed M
Lee, Yujin
Underwood, Martin
Metcalfe, Andrew
Wilkinson, Mark J
Price, Andrew James
Warwick, Jane
Wall, Peter David Henry
author_sort Farhan-Alanie, Muhamed M
collection PubMed
description OBJECTIVE: Tourniquet use in total knee replacement (TKR) is believed to improve the bone-cement interface by reducing bleeding, potentially prolonging implant survival. This study aimed to compare the risk of revision for primary cemented TKR performed with or without a tourniquet. DESIGN: We analysed data from the National Joint Registry (NJR) for all primary cemented TKRs performed in England and Wales between April 2003 and December 2003. Kaplan-Meier plots and Cox regression were used to assess the influence of tourniquet use, age at time of surgery, sex and American Society of Anaesthesiologists (ASA) classification on risk of revision for all-causes. RESULTS: Data were available for 16 974 cases of primary cemented TKR, of which 16 132 had surgery with a tourniquet and 842 had surgery without a tourniquet. At 10 years, 3.8% had undergone revision (95% CI 2.6% to 5.5%) in the no-tourniquet group and 3.1% in the tourniquet group (95% CI 2.8% to 3.4%). After adjusting for age at primary surgery, gender and primary ASA score, the HR for all-cause revision for cemented TKR without a tourniquet was 0.82 (95% CI 0.57 to 1.18). CONCLUSIONS: We did not find evidence that using a tourniquet for primary cemented TKR offers a clinically important or statistically significant reduction in the risk of all-cause revision up to 13 years after surgery. Surgeons should consider this evidence when deciding whether to use a tourniquet for cemented TKR.
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spelling pubmed-81916252021-06-25 Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set Farhan-Alanie, Muhamed M Lee, Yujin Underwood, Martin Metcalfe, Andrew Wilkinson, Mark J Price, Andrew James Warwick, Jane Wall, Peter David Henry BMJ Open Surgery OBJECTIVE: Tourniquet use in total knee replacement (TKR) is believed to improve the bone-cement interface by reducing bleeding, potentially prolonging implant survival. This study aimed to compare the risk of revision for primary cemented TKR performed with or without a tourniquet. DESIGN: We analysed data from the National Joint Registry (NJR) for all primary cemented TKRs performed in England and Wales between April 2003 and December 2003. Kaplan-Meier plots and Cox regression were used to assess the influence of tourniquet use, age at time of surgery, sex and American Society of Anaesthesiologists (ASA) classification on risk of revision for all-causes. RESULTS: Data were available for 16 974 cases of primary cemented TKR, of which 16 132 had surgery with a tourniquet and 842 had surgery without a tourniquet. At 10 years, 3.8% had undergone revision (95% CI 2.6% to 5.5%) in the no-tourniquet group and 3.1% in the tourniquet group (95% CI 2.8% to 3.4%). After adjusting for age at primary surgery, gender and primary ASA score, the HR for all-cause revision for cemented TKR without a tourniquet was 0.82 (95% CI 0.57 to 1.18). CONCLUSIONS: We did not find evidence that using a tourniquet for primary cemented TKR offers a clinically important or statistically significant reduction in the risk of all-cause revision up to 13 years after surgery. Surgeons should consider this evidence when deciding whether to use a tourniquet for cemented TKR. BMJ Publishing Group 2021-06-09 /pmc/articles/PMC8191625/ /pubmed/34108163 http://dx.doi.org/10.1136/bmjopen-2020-045353 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Surgery
Farhan-Alanie, Muhamed M
Lee, Yujin
Underwood, Martin
Metcalfe, Andrew
Wilkinson, Mark J
Price, Andrew James
Warwick, Jane
Wall, Peter David Henry
Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title_full Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title_fullStr Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title_full_unstemmed Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title_short Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
title_sort effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the national joint registry data set
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191625/
https://www.ncbi.nlm.nih.gov/pubmed/34108163
http://dx.doi.org/10.1136/bmjopen-2020-045353
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