m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin

Heterochromatin has essential functions in maintaining chromosome structure, in protecting genome integrity and in stabilizing gene expression programs. Heterochromatin is often nucleated by underlying DNA repeat sequences, such as major satellite repeats (MSR) and long interspersed nuclear elements...

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Detalles Bibliográficos
Autores principales: Duda, Katarzyna J, Ching, Reagan W, Jerabek, Lisa, Shukeir, Nicholas, Erikson, Galina, Engist, Bettina, Onishi-Seebacher, Megumi, Perrera, Valentina, Richter, Florian, Mittler, Gerhard, Fritz, Katharina, Helm, Mark, Knuckles, Philip, Bühler, Marc, Jenuwein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191757/
https://www.ncbi.nlm.nih.gov/pubmed/33999208
http://dx.doi.org/10.1093/nar/gkab364

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