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A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E(z)-like 1) complex, with components conserved in metazoan Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2). The EZL1 complex...

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Detalles Bibliográficos
Autores principales:	Xu, Jing, Zhao, Xiaolu, Mao, Fengbiao, Basrur, Venkatesha, Ueberheide, Beatrix, Chait, Brian T, Allis, C David, Taverna, Sean D, Gao, Shan, Wang, Wei, Liu, Yifan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191774/ https://www.ncbi.nlm.nih.gov/pubmed/33412588 http://dx.doi.org/10.1093/nar/gkaa1262

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