TbTRF suppresses the TERRA level and regulates the cell cycle-dependent TERRA foci number with a TERRA binding activity in its C-terminal Myb domain

Telomere repeat-containing RNA (TERRA) has been identified in multiple organisms including Trypanosoma brucei, a protozoan parasite that causes human African trypanosomiasis. T. brucei regularly switches its major surface antigen, VSG, to evade the host immune response. VSG is expressed exclusively...

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Detalles Bibliográficos
Autores principales: Saha, Arpita, Gaurav, Amit Kumar, Pandya, Unnati M, Afrin, Marjia, Sandhu, Ranjodh, Nanavaty, Vishal, Schnur, Brittny, Li, Bibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191777/
https://www.ncbi.nlm.nih.gov/pubmed/34048580
http://dx.doi.org/10.1093/nar/gkab401

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