Organ-, sex- and age-dependent patterns of endogenous L1 mRNA expression at a single locus resolution

Expression of L1 mRNA, the first step in the L1 copy-and-paste amplification cycle, is a prerequisite for L1-associated genomic instability. We used a reported stringent bioinformatics method to parse L1 mRNA transcripts and measure the level of L1 mRNA expressed in mouse and rat organs at a locus-s...

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Detalles Bibliográficos
Autores principales: Stow, Emily C, Kaul, Tiffany, deHaro, Dawn L, Dem, Madeleine R, Beletsky, Anna G, Morales, Maria E, Du, Qianhui, LaRosa, Alexis J, Yang, Hanlin, Smither, Emily, Baddoo, Melody, Ungerleider, Nathan, Deininger, Prescott, Belancio, Victoria P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191783/
https://www.ncbi.nlm.nih.gov/pubmed/34023901
http://dx.doi.org/10.1093/nar/gkab369

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