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Rcl1 depletion impairs 18S pre-rRNA processing at the A(1)-site and up-regulates a cohort of ribosome biogenesis genes in zebrafish

Yeast Rcl1 is a potential endonuclease that mediates pre-RNA cleavage at the A(2)-site to separate 18S rRNA from 5.8S and 25S rRNAs. However, the biological function of Rcl1 in opisthokonta is poorly defined. Moreover, there is no information regarding the exact positions of 18S pre-rRNA processing...

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Detalles Bibliográficos
Autores principales:	Zhu, Qinfang, Tao, Boxiang, Chen, Hong, Shi, Hui, Huang, Ling, Chen, Jun, Hu, Minjie, Lo, Li Jan, Peng, Jinrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191805/ https://www.ncbi.nlm.nih.gov/pubmed/34019640 http://dx.doi.org/10.1093/nar/gkab381

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