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P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms

The P2X purinoceptor 7 (P2RX7) mediates inflammatory microglial responses and is implicated in neuroimmune mechanisms of depression and neurodegenerative disorders. A number of studies suggest that psychosocial stress may precipitate depression through immune activation. Genetic association studies...

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Detalles Bibliográficos
Autores principales:	Kristof, Zsuliet, Eszlari, Nora, Sutori, Sara, Gal, Zsofia, Torok, Dora, Baksa, Daniel, Petschner, Peter, Sperlagh, Beata, Anderson, Ian M., Deakin, John Francis William, Juhasz, Gabriella, Bagdy, Gyorgy, Gonda, Xenia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191953/ https://www.ncbi.nlm.nih.gov/pubmed/34111150 http://dx.doi.org/10.1371/journal.pone.0252766

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