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Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies
Dozens of incurable neurological disorders result from expansion of short repeat sequences in both coding and non-coding regions of the transcriptome. Short repeat expansions underlie microsatellite repeat expansion (MRE) disorders including myotonic dystrophy (DM1, CUG(50–3,500) in DMPK; DM2, CCTG(...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192115/ https://www.ncbi.nlm.nih.gov/pubmed/33172304 http://dx.doi.org/10.1080/10409238.2020.1841726 |