Cargando…

SARS-CoV-2 mutations altering regulatory properties: Deciphering host's and virus's perspectives

Since the first recorded case of the SARS-CoV-2, it has acquired several mutations in its genome while spreading throughout the globe. In this study, we investigated the significance of these mutations by analyzing the host miRNA binding and virus's internal ribosome entry site (IRES). Striking...

Descripción completa

Detalles Bibliográficos
Autores principales:	Islam, Abul Bashar Mir Md. Khademul, Khan, Md. Abdullah-Al-Kamran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192267/ https://www.ncbi.nlm.nih.gov/pubmed/34131596 http://dx.doi.org/10.1016/j.genrep.2021.101236

Ejemplares similares

SARS-CoV-2 Proteins Exploit Host’s Genetic and Epigenetic Mediators for the Annexation of Key Host Signaling Pathways
por: Khan, Md. Abdullah-Al-Kamran, et al.
Publicado: (2021)

Perversely expressed long noncoding RNAs can alter host response and viral proliferation in SARS-CoV-2 infection
por: Turjya, Rafeed Rahman, et al.
Publicado: (2020)

Epigenetic Regulator miRNA Pattern Differences Among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 World-Wide Isolates Delineated the Mystery Behind the Epic Pathogenicity and Distinct Clinical Characteristics of Pandemic COVID-19
por: Khan, Md. Abdullah-Al-Kamran, et al.
Publicado: (2020)

Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development
por: Islam, Abul Bashar Mir Md. Khademul, et al.
Publicado: (2020)

Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy
por: Islam, Abul Bashar Mir Md. Khademul, et al.
Publicado: (2020)

Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2
por: Islam, Abul Bashar Mir Md. Khademul, et al.
Publicado: (2021)

Targeting SARS-CoV-2 non-structural protein 13 via helicase-inhibitor-repurposing and non-structural protein 16 through pharmacophore-based screening
por: Samdani, Md. Nazmus, et al.
Publicado: (2022)

A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design
por: Sharmin, Refat, et al.
Publicado: (2014)

Modeling of MT. P495, an mRNA-based vaccine against the phosphate-binding protein PstS1 of Mycobacterium tuberculosis
por: Shahrear, Sazzad, et al.
Publicado: (2022)

Mutational profiles of marker genes of cervical carcinoma in Bangladeshi patients
por: Sharmin, Shahana, et al.
Publicado: (2021)

Genomic and evolutionary features of two AHPND positive Vibrio parahaemolyticus strains isolated from shrimp (Penaeus monodon) of south-west Bangladesh
por: Ahmmed, Shawon, et al.
Publicado: (2019)

Functional Analysis of Hypothetical Proteins of Vibrio parahaemolyticus Reveals the Presence of Virulence Factors and Growth-Related Enzymes With Therapeutic Potential
por: Shahrear, Sazzad, et al.
Publicado: (2022)

Drug and Anti-Viral Peptide Design to Inhibit the Monkeypox Virus by Restricting A36R Protein
por: Miah, Mohammad Mohasin, et al.
Publicado: (2022)

Functional Annotation of Hypothetical Proteins From the Enterobacter cloacae B13 Strain and Its Association With Pathogenicity
por: Dey, Supantha, et al.
Publicado: (2022)

Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs
por: Ahmed, Tasmia, et al.
Publicado: (2021)

Host range projection of SARS-CoV-2: South Asia perspective
por: Ahmed, Rasel, et al.
Publicado: (2021)

Mutations in SARS-CoV-2 ORF8 Altered the Bonding Network With Interferon Regulatory Factor 3 to Evade Host Immune System
por: Rashid, Farooq, et al.
Publicado: (2021)

Molecular characterization of duck plague virus from selected Haor areas of Bangladesh
por: Khan, Kamrul Ahmed, et al.
Publicado: (2021)

Artifact suppression and analysis of brain activities with electroencephalography signals
por: Rashed-Al-Mahfuz, Md., et al.
Publicado: (2013)

Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated bioinformatics approaches
por: Ahmed, Fee Faysal, et al.
Publicado: (2022)

Graph Eigen Decomposition-Based Feature-Selection Method for Epileptic Seizure Detection Using Electroencephalography †
por: Molla, Md. Khademul Islam, et al.
Publicado: (2020)

Exploring Prognostic Biomarkers of Acute Myeloid Leukemia to Determine Its Most Effective Drugs from the FDA-Approved List through Molecular Docking and Dynamic Simulation
por: Alom, Md. Murshid, et al.
Publicado: (2023)

Escalating SARS-CoV-2 circulation in environment and tracking waste management in South Asia
por: Islam, Ariful, et al.
Publicado: (2021)

Olfactory and Taste Disorders in Patients with SARS-CoV-2 Infection
por: Begam, Nazia, et al.
Publicado: (2020)

Molecular Epidemiology of SARS-CoV-2 in Diverse Environmental Samples Globally
por: Islam, Ariful, et al.
Publicado: (2021)

Some common deleterious mutations are shared in SARS-CoV-2 genomes from deceased COVID-19 patients across continents
por: Islam, Md. Aminul, et al.
Publicado: (2023)

Major Insights in Dynamics of Host Response to SARS-CoV-2: Impacts and Challenges
por: Hakim, Al, et al.
Publicado: (2021)

Identification of host genomic biomarkers from multiple transcriptomics datasets for diagnosis and therapies of SARS-CoV-2 infections
por: Sarker, Bandhan, et al.
Publicado: (2023)

Chitosan-based nano-sorbents: synthesis, surface modification, characterisation and application in Cd (II), Co (II), Cu (II) and Pb (II) ions removal from wastewater
por: Chandra, Dipesh, et al.
Publicado: (2023)

Vascular Surgery Practice Guidelines during COVID-19 Pandemic in a Setting of High Work Volume Against Limited Resources: Perspective of a Developing Country
por: Bashar, Abul Hasan Muhammad, et al.
Publicado: (2021)

Insights into the SARS-CoV-2-Mediated Alteration in the Stress Granule Protein Regulatory Networks in Humans
por: Prasad, Kartikay, et al.
Publicado: (2021)

Mutational insights into the envelope protein of SARS-CoV-2
por: Rahman, M. Shaminur, et al.
Publicado: (2021)

Incorporating the mutational landscape of SARS-COV-2 variants and case-dependent vaccination rates into epidemic models
por: Chowdhury, Mohammad Mihrab, et al.
Publicado: (2022)

Deciphering the Impact of Mutations on the Binding Efficacy of SARS-CoV-2 Omicron and Delta Variants With Human ACE2 Receptor
por: Khan, Alamgir, et al.
Publicado: (2022)

Prediction of the Effects of Variants and Differential Expression of Key Host Genes ACE2, TMPRSS2, and FURIN in SARS-CoV-2 Pathogenesis: An In Silico Approach
por: Hossain, Md. Shahadat, et al.
Publicado: (2021)

Pharmacokinetics and Bioavailability Study of a Prednisolone Tablet as a Single Oral Dose in Bangladeshi Healthy Volunteers
por: Bashar, Tafsir, et al.
Publicado: (2018)

Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations
por: Kumar, Vijay, et al.
Publicado: (2017)

Altered serum elements, antioxidants, MDA, and immunoglobulins are associated with an increased risk of seborrheic dermatitis
por: Jahan, Ishrat, et al.
Publicado: (2021)

A Computational Study on Selected Alkaloids as SARS-CoV-2 Inhibitors: PASS Prediction, Molecular Docking, ADMET Analysis, DFT, and Molecular Dynamics Simulations
por: Mortuza, Md. Golam, et al.
Publicado: (2023)

SARS-CoV-2 new variant BF.7: a new public threat globally, symptoms, precautions, transmission rate, and futures perspective – correspondence
por: Rahman, Md. Mominur, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h3p2fhbjt7irv84qpucbmqd8ie