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Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer
The measurement of circulating tumour markers (TMs) for the diagnosis or monitoring of breast cancer has sometimes been considered of limited utility. In addition to the overinterpretation of irrelevant changes in marker levels, the characteristics of the patient, the disease or other pathologies th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192375/ https://www.ncbi.nlm.nih.gov/pubmed/33550504 http://dx.doi.org/10.1007/s12094-020-02529-x |
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author | Ayala de la Peña, F. Ortiz-Muñoz, B. Quintanar-Verdúguez, T. Santotoribio, J. D. de la Cruz, S. Trapé-Pujol, J. Galve-Calvo, E. Augé-Fradera, J. M. García-Gómez, J. González-Hernández, Á. |
author_facet | Ayala de la Peña, F. Ortiz-Muñoz, B. Quintanar-Verdúguez, T. Santotoribio, J. D. de la Cruz, S. Trapé-Pujol, J. Galve-Calvo, E. Augé-Fradera, J. M. García-Gómez, J. González-Hernández, Á. |
author_sort | Ayala de la Peña, F. |
collection | PubMed |
description | The measurement of circulating tumour markers (TMs) for the diagnosis or monitoring of breast cancer has sometimes been considered of limited utility. In addition to the overinterpretation of irrelevant changes in marker levels, the characteristics of the patient, the disease or other pathologies that can modify them are often not considered in their evaluation. On the other hand, there are recent data on the relationship of TMs with molecular subtypes and on their prognostic value, the knowledge of which may improve their clinical utility. This consensus article arises from a collaboration between the Spanish Society of Laboratory Medicine (SEQC(ML)) and the Spanish Society of Medical Oncology (SEOM). It aims to improve the use and interpretation of circulating TMs in breast cancer. The text summarizes the current knowledge and available evidence on the subject and proposes a series of recommendations mainly focussed on the indication, the frequency of testing and the factors that should be considered for correctly interpreting changes in the levels of TMs. |
format | Online Article Text |
id | pubmed-8192375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-81923752021-06-28 Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer Ayala de la Peña, F. Ortiz-Muñoz, B. Quintanar-Verdúguez, T. Santotoribio, J. D. de la Cruz, S. Trapé-Pujol, J. Galve-Calvo, E. Augé-Fradera, J. M. García-Gómez, J. González-Hernández, Á. Clin Transl Oncol Special Article The measurement of circulating tumour markers (TMs) for the diagnosis or monitoring of breast cancer has sometimes been considered of limited utility. In addition to the overinterpretation of irrelevant changes in marker levels, the characteristics of the patient, the disease or other pathologies that can modify them are often not considered in their evaluation. On the other hand, there are recent data on the relationship of TMs with molecular subtypes and on their prognostic value, the knowledge of which may improve their clinical utility. This consensus article arises from a collaboration between the Spanish Society of Laboratory Medicine (SEQC(ML)) and the Spanish Society of Medical Oncology (SEOM). It aims to improve the use and interpretation of circulating TMs in breast cancer. The text summarizes the current knowledge and available evidence on the subject and proposes a series of recommendations mainly focussed on the indication, the frequency of testing and the factors that should be considered for correctly interpreting changes in the levels of TMs. Springer International Publishing 2021-02-07 2021 /pmc/articles/PMC8192375/ /pubmed/33550504 http://dx.doi.org/10.1007/s12094-020-02529-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Special Article Ayala de la Peña, F. Ortiz-Muñoz, B. Quintanar-Verdúguez, T. Santotoribio, J. D. de la Cruz, S. Trapé-Pujol, J. Galve-Calvo, E. Augé-Fradera, J. M. García-Gómez, J. González-Hernández, Á. Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title | Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title_full | Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title_fullStr | Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title_full_unstemmed | Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title_short | Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
title_sort | consensus of the spanish society of laboratory medicine and the spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer |
topic | Special Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192375/ https://www.ncbi.nlm.nih.gov/pubmed/33550504 http://dx.doi.org/10.1007/s12094-020-02529-x |
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