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Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
Profiling studies have revealed considerable phenotypic heterogeneity in cancer-associated fibroblasts (CAFs) present within the tumour microenvironment, however, functional characterisation of different CAF subsets is hampered by the lack of specific markers defining these populations. Here we show...
Autores principales: | Jungwirth, Ute, van Weverwijk, Antoinette, Evans, Rachel J., Jenkins, Liam, Vicente, David, Alexander, John, Gao, Qiong, Haider, Syed, Iravani, Marjan, Isacke, Clare M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192501/ https://www.ncbi.nlm.nih.gov/pubmed/34112782 http://dx.doi.org/10.1038/s41467-021-23583-1 |
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