Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

Tissue macrophages self-renew during homeostasis and produce inflammatory mediators upon microbial infection. We examined the relationship between proliferative and inflammatory properties of tissue macrophages by defining the impact of the Wnt/β-catenin pathway, a central regulator of self-renewal,...

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Detalles Bibliográficos
Autores principales: Zhu, Bibo, Wu, Yue, Huang, Su, Zhang, Ruixuan, Son, Young Min, Li, Chaofan, Cheon, In Su, Gao, Xiaochen, Wang, Min, Chen, Yao, Zhou, Xian, Nguyen, Quynh, Phan, Anthony T., Behl, Supriya, Taketo, M. Mark, Mack, Matthias, Shapiro, Virginia S., Zeng, Hu, Ebihara, Hideki, Mullon, John J., Edell, Eric S., Reisenauer, Janani S., Demirel, Nadir, Kern, Ryan M., Chakraborty, Rana, Cui, Weiguo, Kaplan, Mark H., Zhou, Xiaobo, Goldrath, Ananda W., Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192557/
https://www.ncbi.nlm.nih.gov/pubmed/33951416
http://dx.doi.org/10.1016/j.immuni.2021.04.001

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