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Sinisan Protects Primary Hippocampal Neurons Against Corticosterone by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway
Objective: Corticosterone causes significant neurotoxicity in primary hippocampal neurons which is associated with depression. Dysfunctional autophagy is implicated in cognitive impairment and depressive-like behavior. The traditional Chinese medicine Sinisan (SNS) is highly effective in clinical tr...
Autores principales: | Zhang, Mingjia, Zhang, Yi, Sun, Haitao, Ni, Hui, Sun, Jialing, Yang, Xuemei, Chen, Weicong, Zhao, Wenting, Zhong, Xiaodan, He, Chunyu, Ao, Haiqing, He, Songqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192823/ https://www.ncbi.nlm.nih.gov/pubmed/34122166 http://dx.doi.org/10.3389/fpsyt.2021.627056 |
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