Cargando…

Peroxidasin promotes diabetic vascular endothelial dysfunction induced by advanced glycation end products via NOX2/HOCl/Akt/eNOS pathway

Reactive oxygen species (ROS) derived from NADPH oxidases (NOX) plays an essential role in advanced glycation end products (AGEs)-induced diabetic vascular endothelial dysfunction. Peroxidasin (PXDN, VPO1) is one member of peroxidases family that catalyzes hydrogen peroxide (H(2)O(2)) to hypochlorou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jing Cao, Zhang, Guogang, Liu, Zhaoya, Xu, Qian, Li, Chan, Cheng, Guangjie, Shi, Ruizheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192873/ https://www.ncbi.nlm.nih.gov/pubmed/34116361 http://dx.doi.org/10.1016/j.redox.2021.102031

Ejemplares similares

Peroxidasin contributes to lung host defense by direct binding and killing of gram-negative bacteria
por: Shi, Ruizheng, et al.
Publicado: (2018)

Critical role of vascular peroxidase 1 in regulating endothelial nitric oxide synthase
por: Liu, Zhaoya, et al.
Publicado: (2017)

Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4
por: Zhang, Ming, et al.
Publicado: (2013)

The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
por: Alghanem, Ahmad F, et al.
Publicado: (2021)

Total flavonoids from Astragalus alleviate endothelial dysfunction by activating the Akt/eNOS pathway
por: Liu, Qian, et al.
Publicado: (2017)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein
por: Kovács, Hajnal A., et al.
Publicado: (2021)

Endothelial Dysfunction: Is There a Hyperglycemia-Induced Imbalance of NOX and NOS?
por: Meza, Cesar A., et al.
Publicado: (2019)

Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling
por: Zhu, Cuicui, et al.
Publicado: (2017)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

κ-Opioid Receptors Improve Vascular Endothelial Dysfunction in Salt-Sensitive Hypertension via PI3K/Akt/eNOS Signaling Pathway
por: Wu, Qi, et al.
Publicado: (2023)

Increased NOX2 expression in astrocytes leads to eNOS uncoupling through dihydrofolate reductase in endothelial cells after subarachnoid hemorrhage
por: Miao, Shu-Hao, et al.
Publicado: (2023)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway
por: Zhang, Zhiyong, et al.
Publicado: (2020)

Capsaicin Alleviates Vascular Endothelial Dysfunction and Cardiomyopathy via TRPV1/eNOS Pathway in Diabetic Rats
por: Wang, Qiuyue, et al.
Publicado: (2022)

Physiological concentration of protocatechuic acid directly protects vascular endothelial function against inflammation in diabetes through Akt/eNOS pathway
por: Chook, Chui Yiu Bamboo, et al.
Publicado: (2023)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine
por: Xie, Xinya, et al.
Publicado: (2018)

Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress
por: Mahmoud, Ayman M., et al.
Publicado: (2017)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway [Corrigendum]
Publicado: (2020)

Retracted: κ-Opioid Receptors Improve Vascular Endothelial Dysfunction in Salt-Sensitive Hypertension via PI3K/Akt/eNOS Signaling Pathway
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK‐Akt‐eNOS‐NO Pathway in the Spontaneously Hypertensive Rat
por: Fu, Jinjuan, et al.
Publicado: (2016)

Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway
por: Gu, Yang-Yang, et al.
Publicado: (2022)

The Protective Effect of Bcl-xl Overexpression against Oxidative Stress-Induced Vascular Endothelial Cell Injury and the Role of the Akt/eNOS Pathway
por: Ni, Leng, et al.
Publicado: (2013)

Vascular Endothelial Dysfunction in β-Thalassemia Occurs Despite Increased eNOS Expression and Preserved Vascular Smooth Muscle Cell Reactivity to NO
por: Stoyanova, Ekatherina, et al.
Publicado: (2012)

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
por: Zhang, Quan-Jiang, et al.
Publicado: (2012)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Endothelial cell-specific loss of eNOS differentially affects endothelial function
por: Bu, Shuhan, et al.
Publicado: (2022)

Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway
por: Zhou, Caixia, et al.
Publicado: (2022)

Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets
por: Janaszak-Jasiecka, Anna, et al.
Publicado: (2023)

Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice
por: Zhang, Hong, et al.
Publicado: (2022)

High-Mobility Group Box 1 (HMGB1) Induces Migration of Endothelial Progenitor Cell via Receptor for Advanced Glycation End-Products (RAGE)-Dependent PI3K/Akt/eNOS Signaling Pathway
por: Zhang, Yulong, et al.
Publicado: (2019)

Vascular peroxidase 1 is a novel regulator of cardiac fibrosis after myocardial infarction
por: Liu, Zhaoya, et al.
Publicado: (2019)

Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways
por: Zhang, Song, et al.
Publicado: (2019)

High-Fat Diet-Induced Obesity Model Does Not Promote Endothelial Dysfunction via Increasing Leptin/Akt/eNOS Signaling
por: Rocha, Vanessa da Silva, et al.
Publicado: (2019)

Peroxidasin is essential for eye development in the mouse
por: Yan, Xiaohe, et al.
Publicado: (2014)

Molecular Evolution, Structure, and Function of Peroxidasins
por: Soudi, Monika, et al.
Publicado: (2012)

The role of peroxidasin in solid cancer progression
por: Wyllie, Kaitlin, et al.
Publicado: (2023)

Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells
por: Chen, Zhenlong, et al.
Publicado: (2018)

Sex-specific eNOS activity and function in human endothelial cells
por: Cattaneo, Maria Grazia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j52hmtllpcecvrursnvrib5o1p