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Inhibition of angiotensin II type 1 receptor by candesartan reduces tumor growth and ameliorates fibrosis in colorectal cancer
Colorectal cancer (CRC) is an important cause of cancer-related mortality. Aberrant activation of the renin-angiotensin system (RAS) is reported to be associated with poor clinical outcomes in patients with CRC. This study was designed to explore the anti-tumor effects of the angiotensin receptor bl...
Autores principales: | Tabatabai, Ehsan, Khazaei, Majid, Asgharzadeh, Fereshteh, Nazari, Seyedeh Elnaz, Shakour, Neda, Fiuji, Hamid, Ziaeemehr, Aghigh, Mostafapour, Asma, Parizadeh, Mohammad Reza, Nouri, Mohammad, Hassanian, Seyed Mahdi, Hadizadeh, Farzin, Ferns, Gordon A, Rahmati, Mohammad, Rahmani, Farzad, Avan, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192880/ https://www.ncbi.nlm.nih.gov/pubmed/34121975 http://dx.doi.org/10.17179/excli2021-3421 |
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