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Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors
The human norepinephrine transporter (NET) is an established drug target for a wide range of psychiatric disorders. Conventional methods that are used to functionally characterize NET inhibitors are based on the use of radiolabeled or fluorescent substrates. These methods are highly informative, but...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192900/ https://www.ncbi.nlm.nih.gov/pubmed/34112854 http://dx.doi.org/10.1038/s41598-021-91700-7 |