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Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors

The human norepinephrine transporter (NET) is an established drug target for a wide range of psychiatric disorders. Conventional methods that are used to functionally characterize NET inhibitors are based on the use of radiolabeled or fluorescent substrates. These methods are highly informative, but...

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Detalles Bibliográficos
Autores principales:	Sijben, Hubert J., van Oostveen, Wieke M., Hartog, Peter B. R., Stucchi, Laura, Rossignoli, Andrea, Maresca, Giovanna, Scarabottolo, Lia, IJzerman, Adriaan P., Heitman, Laura H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192900/ https://www.ncbi.nlm.nih.gov/pubmed/34112854 http://dx.doi.org/10.1038/s41598-021-91700-7

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