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A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease

Physical activity is of prime importance in non-pharmacological Parkinson’s disease (PD) treatment. The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. A total of 48 PD patients without experience...

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Autores principales: Langer, Agnes, Hasenauer, Sebastian, Flotz, Anna, Gassner, Lucia, Pokan, Rochus, Dabnichki, Peter, Wizany, Laurenz, Gruber, Jakob, Roth, Dominik, Zimmel, Sarah, Treven, Marco, Schmoeger, Michaela, Willinger, Ulrike, Maetzler, Walter, Zach, Heidemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192917/
https://www.ncbi.nlm.nih.gov/pubmed/34112807
http://dx.doi.org/10.1038/s41531-021-00193-8
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author Langer, Agnes
Hasenauer, Sebastian
Flotz, Anna
Gassner, Lucia
Pokan, Rochus
Dabnichki, Peter
Wizany, Laurenz
Gruber, Jakob
Roth, Dominik
Zimmel, Sarah
Treven, Marco
Schmoeger, Michaela
Willinger, Ulrike
Maetzler, Walter
Zach, Heidemarie
author_facet Langer, Agnes
Hasenauer, Sebastian
Flotz, Anna
Gassner, Lucia
Pokan, Rochus
Dabnichki, Peter
Wizany, Laurenz
Gruber, Jakob
Roth, Dominik
Zimmel, Sarah
Treven, Marco
Schmoeger, Michaela
Willinger, Ulrike
Maetzler, Walter
Zach, Heidemarie
author_sort Langer, Agnes
collection PubMed
description Physical activity is of prime importance in non-pharmacological Parkinson’s disease (PD) treatment. The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. A total of 48 PD patients without experience in climbing (average age 64 ± 8 years, Hoehn & Yahr stage 2–3) were assigned either to participate in a 12-week sport climbing course (SC) or to attend an unsupervised physical training group (UT). The primary outcome was the improvement of symptoms on the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III). Sport climbing was associated with a significant reduction of the MDS-UPDRS-III (−12.9 points; 95% CI −15.9 to −9.8), while no significant improvement was to be found in the UT (−3.0 points; 95% CI −6.0 to 0.1). Bradykinesia, rigidity and tremor subscales significantly improved in SC, but not in the unsupervised control group. In terms of feasibility, the study showed a 99% adherence of participants to climbing sessions and a drop-out rate of only 8%. No adverse events occurred. This trial provides class III evidence that sport climbing is highly effective and feasible in mildly to moderately affected PD patients.
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spelling pubmed-81929172021-06-17 A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease Langer, Agnes Hasenauer, Sebastian Flotz, Anna Gassner, Lucia Pokan, Rochus Dabnichki, Peter Wizany, Laurenz Gruber, Jakob Roth, Dominik Zimmel, Sarah Treven, Marco Schmoeger, Michaela Willinger, Ulrike Maetzler, Walter Zach, Heidemarie NPJ Parkinsons Dis Article Physical activity is of prime importance in non-pharmacological Parkinson’s disease (PD) treatment. The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. A total of 48 PD patients without experience in climbing (average age 64 ± 8 years, Hoehn & Yahr stage 2–3) were assigned either to participate in a 12-week sport climbing course (SC) or to attend an unsupervised physical training group (UT). The primary outcome was the improvement of symptoms on the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III). Sport climbing was associated with a significant reduction of the MDS-UPDRS-III (−12.9 points; 95% CI −15.9 to −9.8), while no significant improvement was to be found in the UT (−3.0 points; 95% CI −6.0 to 0.1). Bradykinesia, rigidity and tremor subscales significantly improved in SC, but not in the unsupervised control group. In terms of feasibility, the study showed a 99% adherence of participants to climbing sessions and a drop-out rate of only 8%. No adverse events occurred. This trial provides class III evidence that sport climbing is highly effective and feasible in mildly to moderately affected PD patients. Nature Publishing Group UK 2021-06-10 /pmc/articles/PMC8192917/ /pubmed/34112807 http://dx.doi.org/10.1038/s41531-021-00193-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Langer, Agnes
Hasenauer, Sebastian
Flotz, Anna
Gassner, Lucia
Pokan, Rochus
Dabnichki, Peter
Wizany, Laurenz
Gruber, Jakob
Roth, Dominik
Zimmel, Sarah
Treven, Marco
Schmoeger, Michaela
Willinger, Ulrike
Maetzler, Walter
Zach, Heidemarie
A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title_full A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title_fullStr A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title_full_unstemmed A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title_short A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
title_sort randomised controlled trial on effectiveness and feasibility of sport climbing in parkinson’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192917/
https://www.ncbi.nlm.nih.gov/pubmed/34112807
http://dx.doi.org/10.1038/s41531-021-00193-8
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