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Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Metastatic spread of a cancer to secondary sites is a coordinated, non-random process. Cancer cell-secreted vesicles, especially exosomes, have recently been implicated in the guidance of metastatic dissemination, with specific surface composition determining some aspects of organ-specific localizat...
Autores principales: | Lima, Luize G., Ham, Sunyoung, Shin, Hyunku, Chai, Edna P. Z., Lek, Erica S. H., Lobb, Richard J., Müller, Alexandra F., Mathivanan, Suresh, Yeo, Belinda, Choi, Yeonho, Parker, Belinda S., Möller, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192925/ https://www.ncbi.nlm.nih.gov/pubmed/34112803 http://dx.doi.org/10.1038/s41467-021-23946-8 |
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