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Yeast display of MHC-II enables rapid identification of peptide ligands from protein antigens (RIPPA)

CD4(+) T cells orchestrate adaptive immune responses via binding of antigens to their receptors through specific peptide/MHC-II complexes. To study these responses, it is essential to identify protein-derived MHC-II peptide ligands that constitute epitopes for T cell recognition. However, generating...

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Detalles Bibliográficos
Autores principales: Liu, Rongzeng, Jiang, Wei, Mellins, Elizabeth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193015/
https://www.ncbi.nlm.nih.gov/pubmed/34117370
http://dx.doi.org/10.1038/s41423-021-00717-5